St. Joseph’s Hospital was the original health care facility in Fairbanks and was destroyed by the Chena River flood in 1967. The people of Fairbanks joined together to form the Greater Fairbanks Community Hospital Foundation (The Hospital Foundation) and quickly raised the money for construction of Fairbanks Memorial Hospital (FMH).

FMH opened in 1972 with 116 beds, and the facility was 120,000 square feet in size. In 1976, the North Tower was built to add more bed space and square footage, and in 1977 the intensive care unit was added in order to provide a higher level of care to patients without having to leave Fairbanks. The South Tower was added in 1985 to add space for advanced and growing MRI technology. Denali Center was opened in 1994 to provide short- and long-term health care in a home-like setting.

As a result of a major national shift to outpatient care, the Outpatient Center was expanded in 1996. The state-of-the-art Fairbanks Cancer Treatment Center opened in 2000, providing the first comprehensive cancer treatment in Interior Alaska. It was renamed the J. Michael Carroll Cancer Center in 2011.

In 2003, the new 41,176 square foot East Tower opened to house laboratory, pathology and related departments. Fairbanks Imaging Center was opened in 2005, providing residents with access to state-of-the-art technology and innovative health care. In 2007, the Emergency Department was expanded to better meet the needs of the community. The Cardiology Clinic also opened in 2007, providing the first care of its kind in the Interior. Later that year, the Catheterization Lab opened its doors, allowing patients to receive life-saving procedures without leaving the community.

In 2008, The Hospital Foundation purchased Tanana Valley Clinic, the largest and most comprehensive locally-owned clinic in the state of Alaska. The Harry & Sally Porter Heart Center opened in 2010 and was later renamed Porter Heart & Vascular Center. Hospice services were added in 2012, providing a full circle continuum of health care for the community. In 2015, a two-year modernization and replacement project began for a state-of-the-art surgery center, adding 90,000 square feet to the facility.

In 2016, The Hospital Foundation decided to cut ties with operator Banner Health and operate independently under the newly formed Foundation Health Partners, LLC. Because Fairbanks is the largest, most northern city in Alaska, less than 200 miles from the Arctic Circle, FMH, TVC, and DC serves the entire interior region of Alaska, an area of approximately 250,000 square miles.